Technology stocks were the only sector to rise, but they gave up much of the ground they had won earlier.
The Dow Jones industrial average lost 109 points, or 0.5 percent, to 24,180. The S&P 500 advanced 0.3 percent to 2,636.98.
The S&P 500 rose 7 points, or 0.3 percent, to 2,637.
The Russell 2000 index of smaller-company stocks jumped 11.59, or 0.8 percent, to 1,520.47.
Facebook rose 1.6 percent, Boeing gained 1.9 percent and Wells Fargo climbed 1.9 percent.
Bond prices fell. The yield on the 10-year Treasury rose to 2.38 percent. The Nasdaq composite rose 48 points, or 0.7 percent, to 6,824. Other tech stocks also rose.
British, Irish leaders talk over phone on Brexit border deal
The Government continues to insist it will not change the substance of what it says was agreed with the British government on Brexit earlier this week.
Stocks are closing higher on Wall Street, breaking a four-day losing streak for the Standard & Poor's 500 index.
Chipmaker Broadcom rose 3.1 percent in early trading Thursday after reporting a strong quarter.
The Dow Jones industrial average climbed 82 points, or 0.4 percent, to 24,226. Google parent Alphabet rose 1 percent. The Nasdaq composite rose 25 points, or 0.4 percent, to 6,800.
The Standard & Poor's 500 was little changed at 2,638.
The Dow is up 4,448.88 points, or 22.5 percent.
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