Simmons injured his elbow during the fourth quarter of Wednesday's game against the Portland Trail Blazers while trying to create space for a field-goal attempt.
The rookie will miss his first game of the season due to swelling in his left elbow, per team, first reported by TNT's David Aldridge.
Last year's overall No. 1 draft pick is averaging 18.5 points, 9.1 rebounds and 7.7 assists per game this season.
Trump décline l'offre de Time pour être personnalité de l'année
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Veteran Jerryd Bayless has only just returned to the lineup after missing six games due to a wrist injury.
If healthy after the re-evaluation, Simmons will have the opportunity to go up against LeBron James and the Cleveland Cavaliers on Tuesday.
The Sixers aren't the same team without Ben Simmons, and on Saturday, they'll see exactly what type of team they are this season without their 6-foot-10 point guard. He was in treatment during practice Friday and will be reevaluated Sunday.
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