The corporal, whose name has not been released, was outside of his vehicle when he exchanged gunfire with the driver, state police said.
Police have since confirmed the suspect fled the scene in a auto and drove himself to Easton Hospital.
State Police are confirming one officer was shot during a traffic stop.
Route 33 is closed in both directions near the scene.
Dispatchers reportedly said a blue vehicle with its windows shot out was found near the hospital and a suspect may have entered the hospital with a gunshot wound.
The condition of the shot PA State Police trooper isn't yet known.
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Nazareth Area School District was on lockdown for a short time Tuesday morning because of the shooting.
According to a report by the CBS affiliate in Philadelphia the trooper was airlifted to Saint Luke's Hospital.
"Frances and I are praying for this trooper, the family and every member of the Pennsylvania State Police".
Wilson Area School District has also been put on lockdown. The lockdown has since been lifted.
Gov. Tom Wolf tweeted that he is "praying for this trooper and their family".
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