It affects between five and 10 per cent of all men, according to estimates.
Their study was the first to link the condition to an increased risk of cancer, they claimed.
"Just taking this at face value, clinically this could be interesting because nobody has ever made these associations", Dr Alex Pastuszak told a press briefing, ahead of the American Society of Reproductive Medicine's annual meeting.
Scientists have discovered that men with bends in their penis could be at a higher risk of developing cancer.
Patients with the condition, also known as penile fibrosis, were found to be 40 per cent more likely to get testicular cancer, a 20 per cent increased risk of melanoma and 40 per cent risk of stomach cancer.
Men with Peyronie's disease were 43 per cent more likely to develop stomach cancer, the research claimed.
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"We think this is important because these conditions are largely taken for granted", said Dr Alexander Pastuszak, the leader of the study, according to The Telegraph.
'While they're significant in the sexual and reproductive life-cycles of these patients, linking them to other disorders suggest that these men should be monitored for development of these disorders disproportionately in contrast to the rest of the population'.
The study also analysed men with erectile dysfunction.
They need more research before knowing if Peyronie's could lead to cancer, the researchers further added. The scar tissue region of the erect penis of men with Peyronie's disease does not stretch, thereby bending or becoming disfigured; hence, leading to pain.
At presents, the cause of Peyronie's disease has still not been completely understood.
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