Family has come first for Faf du Plessis‚ who will miss the opening match of South Africa's test series against England at Lord's on Thursday.
Du Plessis has stayed in South Africa to be with wife Imari following the birth of the couple's first child.
In addition to Du Plessis' absence, South Africa are without pace bowler Dale Steyn, who has not recovered from a shoulder injury, and former captain AB de Villiers, who is taking a break from Test cricket.
South Africa team manager Dr Mohammed Moosajee said: "Faf's wife gave birth to their first child last week, but the hard nature of the delivery has delayed his return to the United Kingdom". "He will link up with the squad in the United Kingdom later this week".
Eric Besson va prendre la tête d'un club de football
L'ancien ministre de l'Identité nationale sous Nicolas Sarkozy, Eric Besson, est connu pour être fan de football. Un ancien ministre à la tête du BMSF, le club de football du Blanc-Mesnil.
Du Plessis will rejoin the squad later in the week to prepare for the second Test at Trent Bridge which begins on July 14.
De Bruyn had made his debut in March against New Zealand after Stephen Cook was dropped from the opening slot. Heino Kuhn is set to partner stand-in skipper Elgar at the top of the order which means half of South Africa's top four will be fairly inexperienced.
The experienced paceman had been a doubt for the first of four matches against Joe Root's side after struggling with an ankle injury sustained in the County Championship with Sussex.
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