Dan Biggar replied 12 minutes later after both Tommy Seymour and Rhys Webb were stopped on the line, but it was the home side who grabbed the opening try.
"I'm gutted to be leaving to be leaving the Tour at this stage", Hogg said as the Lions prepared to face Highlanders In Dunedin on Wednesday (AEST).
The Highlanders were playing the game at a relentless pace and Waisake Naholo showed tremendous power to score the game's first try, bursting through the challenges of Jared Payne and Courtney Lawes to touch down. Sopoaga converted and the hosts had a 10-3 lead.
A home team missing nine first-choice players were outscored three tries to two in an even and fast-paced affair.
But the Lions hit straight back using a well-organised driving maul.
Jonathan Joseph levels the score with a try for the Lions.
The Lions finally found their attacking mojo, scoring three tries to two - more than doubling their try tally so far - but lost from a winning position through a late penalty.
Lions captain Sam Warburton:"For one reason or another the penalties got up into double figures".
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When a ref is hit by a puck or caught amid the scrum of the players, it is a momentary jolt, a tear in the flow of the sport. Say what you will about Nashville's explosiveness, but the Predators sorely missed Ryan Johansen's scoring touch.
Biggar couldn't convert this time and an unnecessary shoulder charge from Kyle Sinckler allowed Sopoaga and the Highlanders to close the gap to only two points with the successful penalty.
Centre Robbie Henshaw, meanwhile, says he is "extremely frustrated" to have been involved in two defeats in a Lions shirt.
Highlanders replacement first five Marty Banks got the Highlanders back in front with six minutes left on the clock through a penalty 30m out from the goal posts.
"The players mentioned it in the changing room afterwards that at 22-13 they felt comfortable but the thing about New Zealand teams is that they play for the full 80 minutes and they keep putting you under pressure", he said.
Wide boys - The Highlanders looked to get the ball into the wide channels quickly with long passes and also used grubber kicks towards the touchlines to find space to the edges or behind the Lions defensive line.
HIGHLANDERS: R Buckman; W Naholo, M Fekitoa (M Banks, 11-16), T Walden, T Li (P Osborne, 68); L Sopoaga (M Banks, 55), K Hammington (J Renton, 76); D Leinert-Brown (A Seiuli, 59), L Coltman (G Pleasants-Tate, 68), S Tokolahi (S Halanukonuka, 68); A Ainley (J Dickson, 55), J Hemopo; G Evans, D Hunt (J Lentjes, 59), L Whitelock - captain. There was a brilliant dummy and surge in the first half that released Jack Nowell before the move broke down, and he again confused the Highlanders defence a few minutes later in their 22.
Elliot Daly attempts to win it for the Lions.
The Lions wanted the penalty reversed amid tetchy jostling after the scrum, but TMO Marius Jonker told referee Gardner: "They were just all saying hello and goodnight to one another".
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